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This paper deal about using health informatics in medical praxis. In the present time is starts in European Union the New Health National Strategy program. Concept of health informatics includes a lot of application areas and solutions, aiming to increase quality and efficacy of health care. By integrating the informatics technologies in medicine increased the effectivity for diagnostic and treatment of patients. In meaning of eHealth we present four research cases - scoliosis diagnostic, measurement of intra-abdominal pressure, measurement of total hip endoprosthesis wearing and mechanical testing of biological tissue.