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Wireless interference can make a significant impact on the performance of a wireless network. The paper studies TDMA-based timeslot allocation to schedule links efficiently under RTS/CTS interference model of wireless networks, and presents an efficient centralized timeslot assignment algorithm. In addition, the paper presents an effective heuristic algorithm for calculating end-to-end bandwidth on a path, which is used together with AODV to setup QoS routes. Simulation results show that compared with the shortest path routing, our interference-aware QoS routing algorithm increases success ratio of finding a route with required bandwidth to destination node.