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This paper reformulates the multi-user OFDMA resource allocation problems in broadcast and multiple-access channels by defining an equivalent interference channel. The resulting problems are then solved by employing low-complexity algorithms for spectrum optimization in the interference channel. The re-formulation averts the high-complexity integer programming problem that otherwise results from an OFDMA system that allocates each user to separate subchannels. Simulation results indicate that the proposed algorithm achieves near-optimal performance and is suitable for PLC resource allocation applications.