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Chemical bionics - a novel design approach using Ion Sensitive Field Effect Transistors

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2 Author(s)
Georgiou, P. ; Inst. of Biomed. Eng., Imperial Coll. London, London ; Toumazou, C.

This paper introduces Chemical Bionics in which the biochemical physiology of cells in the body are implemented in VLSI to make novel bio-inspired therapeutic devices. As an example, the glucose dependant electrophysiology of the pancreatic beta cell is implemented in silicon to form a novel bio-inspired prosthetic for glucose homeostasis of Type I diabetes. For this, the Ion Sensitive Field Effect Transistor (ISFET) is shown as a suitable chemical sensing front end, which allows CMOS monolithic implementation, as well as low power weak-inversion operation.

Published in:

Biomedical Circuits and Systems Conference, 2008. BioCAS 2008. IEEE

Date of Conference:

20-22 Nov. 2008