By Topic

Positron emission mammography (PEM): a promising technique for detecting breast cancer

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Thompson, C.J. ; Neurological Inst., McGill Univ., Montreal, Que., Canada ; Murthy, K. ; Picard, Y. ; Weinberg, I.N.
more authors

We are developing a high specificity technique for detecting the increased metabolic rate of breast tumours. The glucose analog FDG is known to concentrate in breast tumours rendering them easily detectable in conventional PET scans. Since PET is a relatively expensive imaging technique it has not been used routinely in the detection of breast cancer. Positron emission mammography (PEM) will provide a highly efficient high spatial resolution and low cost positron imaging system whose metabolic images are co-registered with conventional mammography. Coincidences between two BGO blocks cut into 2×2 mm squares coupled to two 7.5 cm square imaging PMTs are detected and back-projected to form real-time multiple plane images. The design is about 20 times more sensitive than a conventional multi-slice PET body scanner, so much less radio-pharmaceutical can be used, reducing the patient dose and cost per scan. Prototype detectors have been made and extensive measurements done. The device is expected to have an in-plane spatial resolution about 2 mm FWHM. Besides the application as a secondary screening tool the device may be beneficial in measuring a tumour's response to radio-therapy or chemo-therapy, as well as aiding the surgeon in optimizing the removal of malignant tissue

Published in:

Nuclear Science, IEEE Transactions on  (Volume:42 ,  Issue: 4 )