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A joint channel estimation and data detection scheme by using Markov chain Monte Carlo (MCMC) is proposed for MIMO-OFDM systems with multi-tone narrow-band interference (MTNBI). The channel impulse response, the noise variance and the indicator of the impulse noise can be estimated accurately, and then the receiver knows whether the signal is interfered by the narrow band interference. One of the most attractive advantages of MCMC method is that it can cooperate with soft-input soft-output decoding, and thus it can be used in turbo detection. Simulation results show that the proposed receiver can approach the performance of the receiver with ideal channel state information under the slow fading channel.