By Topic

A two-stage neural network based technique for protein secondary structure prediction

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Rajasekhar Kakumani ; Department of Electrical and Computer Engineering, Concordia University, 1455 de Maisonneuve Blvd. West, Montreal, H3G1M8, Quebec, Canada ; Vijay Devabhaktuni ; M. Omair Ahmad

Protein secondary structure prediction is one of the most important research areas in bioinformatics. In this paper, we propose a two-stage protein secondary structure prediction technique, implemented using neural network models. The first neural network stage of the proposed technique associates the input protein sequence to a bin containing its corresponding homologues. The second stage predicts the secondary structure of the input sequence utilizing a neural prediction model specific to the bin obtained from stage one. The strategy of binning allows for simplified and accurate neural models. This technique is implemented on the RS126 dataset and its prediction accuracy is compared with that of the standard PHD approach.

Published in:

2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Date of Conference:

20-25 Aug. 2008