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In this paper, we focus on the general relay channel. We investigate the application of the estimate-and-forward (EAF) relaying scheme to different scenarios. Specifically, we study assignments of the auxiliary random variable that always satisfy the feasibility constraints. We then consider the Gaussian relay channel with coded modulation, where we show that a three-level quantization outperforms the Gaussian quantization commonly used to evaluate the achievable EAF rates in this scenario. Last, we consider the cooperative general broadcast scenario with a multistep conference between the receivers. We first apply EAF to obtain a general achievable rate region with a multistep conference. We then use an explicit assignment for the auxiliary random variables to obtain an explicit rate expression for the single common message case with a two-step conference.