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In (S. Wang et al., 2006), an evolution strategy (ES) multiuser detector was proposed and exhibits good performance. This letter analyzes the search behavior of the ES detector and points out it can be greatly enhanced via a simple technique. A heuristic multiuser detection algorithm is presented, which employs the neighborhood structure characteristics of the optimum multiuser detection (OMD) problem and produces local optima efficiently. A well-chosen perturbation strategy is applied to improve the solution quality in the following step. Simulations results show the meta-heuristic algorithm proposed can find the (near) optimum solution rapidly with lower computational complexity and has better bit error rate (BER) performance.