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This paper discuss the role of Web 2.0 in building the distributed electronic infrastructure for science, business, consumer and government applications. We compare functionality of Web 2.0 technologies with those of Grids for API's, messaging, composition (workflow) and portals. We discuss Gadgets, AJAX, JSON and Mashups as core Web 2.0 technologies. We also review the functionality of Web 2.0 services such as Google Maps, Start pages, Community bookmarking and social networking sites and compare with those from Grid and P2P. We look at security, management and other capabilities where the robustness of Grids could be critical.