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MRI-based magnetic navigation of nanomedical devices for drug delivery and hyperthermia in deep tissues

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2 Author(s)
Mathieu, Jean-Baptiste ; Dept. of Comput. Eng. & Inst. of Biomed. Eng., Campus of the Univ. de Montreal, Montreal, QC ; Martel, S.

Magnetic resonance imaging (MRI) scanners can be used with minimum upgrades as integrated platforms for targeted delivery of micro/nanoparticles in the human body. In addition to being widespread in hospitals, they provide real-time tracking, control and means of propulsion for magnetic devices without penetration depth limitations. From these positive features, MRI appears as the perfect central element of a nanomedical navigation platform. Nevertheless, these assets are also coupled with constraints arising from the use of an already existing interventional platform. Potential magnetic nanoparticles-based carriers with the navigation platform are described. A simple magnetic suspension model taking magnetic dipole-dipole interactions into account is also proposed.

Published in:

Nanotechnology, 2007. IEEE-NANO 2007. 7th IEEE Conference on

Date of Conference:

2-5 Aug. 2007