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An asymmetrical wireless interface and transceiver designed for implanted medical image applications are reported. The proposed system operated at the 402-405 MHz MICS (medical implantable communication system) band, and it utilizes different modulation schemes for uplink and downlink to lower power consumption and reduce circuit implementation complexity. A high data rate (524 kbps within 300-kHz channel and maximum 1.5 Mbps) and low-power (12.7 mW) direct-modulation FSK transmitter is proposed for medical image transmission, and a low-power (3.3 mW) superregenerative OOK receiver is adopted for command receiving. The wireless interface design considerations and key circuit realizations are presented in this paper.