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Three-dimensional motion of a nanoparticle on the cell membrane observed by non-interferometric widefield optical profilometry

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6 Author(s)
Chau-Hwang Lee ; Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan ; Chun-Chieh Wang ; Chia-Wei Lee ; Chia-Yun Huang
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We directly observe three-dimensional motion of a gold nanoparticle on the membrane of a living cell by using non-interferometric widefield optical profilometry. We identify the occurrence of particle internalization and actin aggregation which indicates endocytosis.

Published in:

Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on

Date of Conference:

4-9 May 2008