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Human age prediction is useful for many applications. The age information could be used as a kind of semantic knowledge for multimedia content analysis and understanding. In this paper we propose a probabilistic fusion approach (PFA) that produces a high performance estimator for human age prediction. The PFA framework fuses a regressor and a classifier. We derive the predictor based on Bayespsila rule without the mutual independence assumption that is very common for traditional classifier combination methods. Using a sequential fusion strategy, the predictor reduces age estimation errors significantly. Experiments on the large UIUC-IFP-Y aging database and the FG-NET aging database show the merit of the proposed approach to human age prediction.