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BOGENVI: A Biomedical Ontology for Modelling Gene*Environment Interactions on Intermediate Phenotypes in Nutrigenomics Research

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6 Author(s)
Antonio Fabregat ; Dept. of Comput. Languages & Syst., Univ. Jaume I, Castellon de la Plana ; Elisabet Barrera ; María Arregui ; Olga Portolés
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Nutritional Genomics is demanding computing models and technological platforms in order to support acquisition, storage, management and presentation of all the information generated coming from heterogeneous sources: genotypes, environmental factors (diet and other life-style factors) and phenotypes (intermediate and final phenotypes). Our aim is to build a biomedical ontology in order to modelling gene*environment interactions on intermediate phenotypes by means of formalising and integrating genomic, environmental and phenotypic data, in the field of research on Nutritional Genomics applied to cardiovascular diseases and associated phenotypes. This ontology is part of a Health Information System based on Web engineering technologies, architectures and services, and integrating several data types to support Nutritional Genomics research in cardiovascular diseases.

Published in:

Computer-Based Medical Systems, 2008. CBMS '08. 21st IEEE International Symposium on

Date of Conference:

17-19 June 2008