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Classification performance on a population with contexts

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4 Author(s)
Choudhary, A. ; Translational Genomics Res. Inst., Phoenix, AZ ; Jianping Hua ; Bittner, M.L. ; Dougherty, E.R.

Several classification studies have been conducted to relate molecular expression to disease progression, outcome and vulnerability. These studies have failed except in simple situations. A reason for this has been that classification schemes have in general ignored the heterogeneity of underlying cellular contexts. In this work we conduct a model based study to demonstrate and quantify how existence of contexts degrades classification performance.

Published in:

Genomic Signal Processing and Statistics, 2008. GENSiPS 2008. IEEE International Workshop on

Date of Conference:

8-10 June 2008