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There is an increasing need to develop more flexible and intelligent low power wireless body sensor network (WBSN) system for healthcare monitoring applications. Technical advancements in micro-sensors, micro electro- mechanical system (MEMS) devices, low power electronics, and radio frequency (RF) circuits and systems have enabled both design and development of such highly integrated system. In this paper, we present a wireless body sensor network system with the capability of variable resolution function, which enables several resolutions for users selecting. The four levels hierarchical architecture is working well with communication system and control system. The accurate pipeline control will make implement variable resolution design in WBSN system easily and advance the performance efficiently. A variable sample rate generator is designed in each sensor node for producing different sample signals to ADC for variable resolutions. The SNR of ECG can be promoted from 25 dB to 73 dB when extraordinary situation of ECG occurs.