By Topic

Preparation of Composite Conducting Materials and its Application to Glucose Biosensor

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Xiangzhong Ren ; Coll. of Chem. & Chem. Eng., Shenzhen Univ., Shenzhen ; Yingkai Jiang ; Xun Liang ; Jianhong Liu
more authors

Copper-mediated graft-copolymerization of methyl methacrylate (MMA) onto casein was studied in this paper. The casein-g-PMMA was isolated by solvent extraction and was identified by Fourier transform infrared spectra (FTIR). Transmission electron microscope (TEM) micrographs revealed the presence of core-shell particles where PMMA was the core and casein was the shell. A glucose oxidase electrode with immobilizing carriers of casein-g-PMMA and polypyrrole membrane was prepared by a multiple-step electrochemically polymerization. The effects of reaction conditions such as working voltage, glucose concentration, temperature and solution pH on the characteristics of electrode bioelectrochemical response were discussed. The sensitivity and stability of the electrode were also investigated. Experimental results showed that the multiple enzyme electrode's linear range was 1.0 times 10-6~ 1.43 times 10-2 mol/L and the detection limit was 1.0 times 10-7mol/L, the stable response time was 8 seconds. The electrode exhibited favorable repeatability and selectability, and its lifetime was greater than one month. The glucose biosensor will have a widest application in clinical diagnosis.

Published in:

Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on

Date of Conference:

16-18 May 2008