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Small-World Network Approach to Identify Nucleus Residues of the B1 Domain of Protein G#

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5 Author(s)
Hai-yan Li ; Key Lab. of Biophys., Univ. of Shandong Province, Dezhou ; Ji-Hua Wang ; Li-ling Zhao ; Xiang-hua Dou
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The B1 domain of protein G is a paradigm for kinetics studies. In this work, the protein structure of GB1 is modeled as an unweighted amino acid network. We find that the unweighted amino acid network is the typical property of small-world network. The nucleus residues of GB1 are identified by the analysis of the network parameter: betweenness. The results are consistent with the previous experimental and theoretical studies.

Published in:

Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on

Date of Conference:

16-18 May 2008