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A novel algorithm is proposed to calculate a solution for cross-layer optimization (CLO) between application (APP) layer and medium access control (MAC) layer. The CLO problem is analyzed mathematically and for a related similar optimization problem an explicit solution is found. Based on this solution a deterministic iterative algorithm is deducted, which can approximate the solution of the original problem with little complexity in an upper bounded number of steps. There is an easy way to adapt the algorithm to different objectives, e.g., to maximize the sum of the users' mean opinion scores (MOS) or to limit the outage of users. Multiple examples are given and simulation results are provided.