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In this paper we propose an optimization of MAC protocol design for wireless sensor networks, that accounts for cross-layering information. In particular, we look at integrating location information with backoff window design for a MAC protocol. While location information is many times crucial for the relevance of the reported event in sensor networks, location estimation algorithms do not always yield accurate information. The estimation accuracy can be characterized spatially using a location reliability probability distribution function. We show that this distribution function greatly influences the design of the optimal backoff window parameters, and the overall throughput performance of the MAC protocol.