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Texture classification using nonlinear color quantization: Application to histopathological image analysis

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7 Author(s)
Olcay Sertel ; Department of Electrical and Computer Engineering, The Ohio State University, Columbus, 43210, USA ; Jun Kong ; Gerard Lozanski ; Arwa Shana'ah
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In this paper, a novel color texture classification approach is introduced and applied to computer-assisted grading of follicular lymphoma from whole-slide tissue samples. The digitized tissue samples of follicular lymphoma were classified into histological grades under a statistical framework. The proposed method classifies the image either into low or high grades based on the amount of cytological components. To further discriminate the lower grades into low and mid grades, we proposed a novel color texture analysis approach. This approach modifies the gray level cooccurrence matrix method by using a nonlinear color quantization with self-organizing feature maps (SOFMs). This is particularly useful for the analysis of H&E stained pathological images whose dynamic color range is considerably limited. Experimental results on real follicular lymphoma images demonstrate that the proposed approach outperforms the gray level based texture analysis.

Published in:

2008 IEEE International Conference on Acoustics, Speech and Signal Processing

Date of Conference:

March 31 2008-April 4 2008