By Topic

A Servo-Controlled, Whole Body, Blood Perfusion System as a Pressure/Flow Clamp

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

2 Author(s)
Shirer, H.W. ; Dept. of Comparative Biochemistry and Physiology and the Dept. of Electrical Engineering, University of Kansas, Lawrence, Kans. ; Jochim, K.E.

To study the peripheral vascular system of anesthetized dogs, a whole body, blood perfusion system was developed to provide 1) a nonpulsatile output of 2) constant pressure (0-300 mm Hg), or 3) constant flow (0-3 liters/minute), or 4) any output characteristic between these extremes, and 5) the output controllable from a voltage command signal. Output is determined by pneumatic pressure, adjusted by a servo valve from the error signal, which drives the blood from a reservoir into the animal's aorta. The error signal is derived from the difference between either a flowmeter or pressure-gage signal and an adjustable set-point voltage, or any combination of these signals. Response time is less than 1 sec. Heat and gas exchange are provided by a double-walled disk oxygenator. Plasma hemoglobin accumulation is typically 0.2 mg/ml hour.

Published in:

Biomedical Engineering, IEEE Transactions on  (Volume:BME-11 ,  Issue: 3 )