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Noise Correction on Rician Distributed Data for Fibre Orientation Estimators

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6 Author(s)
Clarke, R.A. ; Dept. of Nucl. Med., San Raffaele Sci. Inst., Milan ; Scifo, P. ; Rizzo, G. ; Dell'Acqua, F.
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New complex tissue microstructure estimators have been presented recently in order to elucidate white matter fibre orientations. Since these algorithms are based on the diffusion- weighted signal profile, the estimations are affected by noise artefacts. The proven robustness of these methods cannot counteract distortions since the statistical Rician behavior has not been taken into account. In this study, two techniques to counteract the noise distortions are presented to improve the fibre orientation estimations. Simulations and in vivo experiments show an improvement in the angular resolution and convergence of the results. One of these strategies represents a good compromise between computational cost and result improvements.

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Medical Imaging, IEEE Transactions on  (Volume:27 ,  Issue: 9 )