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Cell Trapping in Activated Micropores for Functional Analysis

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7 Author(s)
Talasaz, A.A.H. ; Electr. Eng. Dept., Stanford Univ., CA ; Powell, A.A. ; Stahl, P. ; Ronaghi, M.
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This paper presents a novel device which provides the opportunity to perform high-throughput biochemical assays on different individual cells. In particular, the proposed device is suited to screen the rare cells in biological samples for early stage cancer diagnosis and explore their biochemical functionality. In the process, single cells are precisely positioned and captured in activated micropores. To show the performance of the proposed device, cultured yeast cells and human epithelial circulating tumor cells are successfully captured

Published in:

Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE

Date of Conference:

Aug. 30 2006-Sept. 3 2006