By Topic

Impedance Analysis of HL-60 Cells Uptake of Au Nanoparticles by Using DEP Chip with Multi-layer Electrodes and SU-8 Microstructures

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Chuang, C.H. ; Southern Taiwan Univ. of Tech., Tainan ; Wei, C.H. ; Hsu, Y.M. ; Lu, J.T.
more authors

In this study, a DEP chip with multi-layer electrodes and microcavities array was designed for trapping cells and further impedance measurement. The capability of trapping cells can be achieved single-cell level and without overlapping due to the effects of SU-8 microcavities. However, the depth of microcavity also could affect the results of impedance measurement owing to the insulation layer of SU-8. Two kinds of DEP chip with different thickness of SU-8 layer were, therefore, fabricated and performed to investigate the microstructural effects on impedance measurement. By using this microchip, we can easily identify whether cells (HL-60) are uptaken of Au nanoparticles or not according to the impedance spectrum. Consequently, this method provides an alternative way to separate normal cells and cells uptake of nanoparticles for further inspection.

Published in:

Microprocesses and Nanotechnology, 2007 Digest of papers

Date of Conference:

5-8 Nov. 2007