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High-Throughput Endpoint and Real-Time Detection of Biochemical Reactions in Microarrays Using Label-Free Oblique-Incidence Reflectivity Difference Microscopes

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4 Author(s)
Landry, J.P. ; Univ. of California at Davis, Davis ; Sun, Y.S. ; Lam, K.S. ; Zhu, X.D.

We describe recently developed oblique-incidence reflectivity difference microscopes, a form of polarization-modulated imaging ellipsometry, for label-free detection of biochemical reactions in microarrays. Configurations enabling high-throughput endpoint and real-time detection on glass substrates are discussed.

Published in:

Lasers and Electro-Optics, 2007. CLEO 2007. Conference on

Date of Conference:

6-11 May 2007