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Tutorial on Photoacoustic Microscopy and Computed Tomography

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1 Author(s)
Wang, L.V. ; Washington Univ., St. Louis

The field of photoacoustic tomography has experienced considerable growth in the past few years. Although several commercially available pure optical imaging modalities, including confocal microscopy, two-photon microscopy, and optical coherence tomography, have been highly successful, none of these technologies can provide penetration beyond ~1 mm into scattering biological tissues, because they are based on ballistic and quasi-ballistic photons. Heretofore, there has been a void in high-resolution optical imaging beyond this penetration limit. Photoacoustic tomography, which combines high ultrasonic resolution and strong optical contrast in a single modality, has broken through this limitation and filled this void. In this paper, the fundamentals of photoacoustics are first introduced. Then, scanning photoacoustic microscopy and reconstruction-based photoacoustic tomography (or photoacoustic computed tomography) are covered.

Published in:

Selected Topics in Quantum Electronics, IEEE Journal of  (Volume:14 ,  Issue: 1 )

Date of Publication:

Jan.-feb. 2008

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