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Wireless body area network for sensing and monitoring of vital signs is the one of most rapid growing wireless communication system. A key component of wireless body area network is an antenna. It must meet biocompatible and size- limit requirements. Therefore, antenna for wireless body area network faces numerous RF challenges. We used an antenna with two layers of substrate to cancel the effect of human body on antenna performance. In this paper we present an UWB antenna performance in the free space, on direct contact with human body and way out to reduce the effect of human body on antenna performance without any changes on antenna design.