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Diagnosis of Cervical Intraepithelial Neoplasm (CIN) Using Polarization-Sensitive Optical Coherence Tomography

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10 Author(s)
Sang-Won Lee ; Dept. of Biomedical Engineering, Yonsei University, 234 Maeji, Heungup, Wonju, Gangwon, KOREA, Dept. of Pathology, Yonsei University, 162 Ilsan, Wonju, Gangwon, KOREA, Dept. of Obstetrics and Gynecology, Yonsei University, 162 Ilsan, Wonju, Gangwon, KOREA, MTC Medical Inc., Seoul, KOREA ; Ji-Young Yoo ; Jin-Ho Kang ; Moon-Sik Kang
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We used the polarization-sensitive optical coherence tomography (PS-OCT) to measure the degrees of circular polarization (DOCP) in human cervix. It was found that DOCP measurements are sensitive to the tissue scattering changes caused by the cervical intraepithelial neoplasia. The sensitivity and specificity of the PS-OCT diagnosis were 94.4 and 90.6%.

Published in:

Lasers and Electro-Optics - Pacific Rim, 2007. CLEO/Pacific Rim 2007. Conference on

Date of Conference:

26-31 Aug. 2007