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Continuous measurement of intraocular pressure is important in the detection and treatment of glaucoma. While a point check of intraocular pressure in a doctor's office using indirect measurements such as the tonometer is helpful, it is inadequate to track circadian variation. Circadian variation is an independent risk factor in addition to elevated pressure levels. This paper is aimed at providing an up-to-date review of various intraocular pressure sensing techniques and in vivo sensor design approaches. The basic operating principles of various implantable sensors are reviewed and categorized into groups to delineate their differences. A discussion is presented identifying the drawbacks of existing designs and key design questions are proposed for future progress.
Date of Publication: Jan. 2008