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Linear Predictive Coding for Enhanced Microarray Data Clustering

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3 Author(s)
Istepanian, R.S.H. ; Kingston Univ. Kingston-Upon-Thames, Kingston upon Thames ; Sungoor, Ala ; Nebel, J.-C.

Microarrays are powerful tools for simultaneous monitoring of the expression levels of large number of genes. Their analysis is usually achieved by using clustering techniques. In this paper, we present a new clustering method based on Linear Predictive Coding to provide enhanced microarray data analysis. In this approach, spectral analysis of microarray data is performed to classify samples according to their distortion values. The technique was validated for a standard data set. Comparative analysis of the results indicates that this method provides improved clustering accuracy compared to some conventional clustering techniques. Moreover, our classifier does not require any prior training procedure.

Published in:

Genomic Signal Processing and Statistics, 2007. GENSIPS 2007. IEEE International Workshop on

Date of Conference:

10-12 June 2007