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JAIST (Japan Advanced Institute of Science and Technology) established a unique MOT course in 2003 in Tokyo, which framework was structured on the base of "knowledge science". The graduate school of knowledge science was established in 1096, by the first dean, Prof. Ikujiro Nonaka, a distinguished leader of knowledge creation management. The JAIST-MOT course focused its goal to innovation management and to educate technology based innovators to be called "techno-producer" who has capabilities of concept generation, coordination, and project management. This MOT program introduced many new subjects such as strategic roadmapping, concept generation, services sciences that empower the competence of next-generation MOT or next-generation innovation management. This paper reviews the JAIST-MOT concept, characteristics of the programs, implementation process, resulting performance of about three-year practices and the future perspectives.