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This paper contributes a framework for dealing with complex, technical program transitions. This paper offers a framework of strategic management tools. Tools such as scenario planning, organizational roadmaps, objectives, and measures are integrated into a systematic planning process. Using the KSC response to the new NASA Vision for Space Exploration, this paper offers a framework of strategy tools that leads from initial analysis to the business plan. An engineering manager can use this paper to follow a simple set of steps and tools to help manage strategy for an organizational transformation.