Cart (Loading....) | Create Account
Close category search window
 

Brain PET Partial-Volume Compensation Using Blurred Anatomical Labels

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Bataille, F. ; Dept. of Frederic Joliot Hosp., Commissariat a lEnergie Atomique, Orsay ; Comtat, C. ; Jan, S. ; Sureau, F.C.
more authors

Clinical use of positron emission tomography (PET) for brain imaging is limited by the partial-volume effect (PVE) induced by the limited spatial resolution of most scanners. Correction for this effect is often performed using a post-reconstruction processing framework involving external information provided by an MRI acquisition. This approach has the major drawback of being very sensitive to the unavoidable MRI segmentation and PET-MRI registration mismatches. Under the assumption that PVE is better compensated when it is modeled in the reconstruction process, we developed in this work an approach based on the combined usage of a realistic system response function and of a Bayesian framework allowing the incorporation of the external information in the reconstruction process through the blurred anatomical labels method. PVE compensation performance of the proposed methodology was validated on a phantom double-isotope acquisition, in comparison with the post-reconstruction correction method of the geometric transfer matrix (GTM). A Monte Carlo simulation of a realistic brain PET study allowed us to show the performances of our method relative to the residual mismatches mentioned above.

Published in:

Nuclear Science, IEEE Transactions on  (Volume:54 ,  Issue: 5 )

Date of Publication:

Oct. 2007

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.