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Maximum-Likelihood Reconstruction for Single-Photon Emission Computed-Tomography

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3 Author(s)
Miller, M.I. ; Department of Electrical Engineering, Institute for Biomedical Computing ; Snyder, Donald L. ; Miller, Tom R.

A mathematical model is formulated for a gamma camera used to observe single-photon emissions from multiple view angles. The model accounts for the statistics of radioactive decays, nonuniform attenuation, and a depth-dependent point-spread function. The maximum-likelihood method of statistics is used with the model to derive an algorithm for estimating the distribution of radioactivity.

Published in:

Nuclear Science, IEEE Transactions on  (Volume:32 ,  Issue: 1 )