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Real-Time Image Reconstruction for Time-of-Flight Positron Emission Tomography (TOFPET)

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4 Author(s)
Philippe, E.A. ; University of Texas Medical School at Houston, Division of Cardiology, 6431 Fannin, Houston, TX 77030 ; Mullani, N. ; Wong, W. ; Hartz, R.

Several researchers have proven the benefits of using time-of-flight data in Positron Emission Tomography (TOFPET). One of the characteristics of TOFPET which has not been previously explored is the ability to carry out real-time image reconstruction. The advantages of real-time reconstruction are four-fold: 1) Immediate visual feedback of image build-up, 2) Substantial savings of image memory, 3) Faster thoughput of patients through the system and 4) Region-of-interest reconstruction for further memory savings. We present a generalized mathematical model describing this technique together with computer simulations demonstrating its feasibility. We also discuss the implementation of this real-time reconstruction scheme in the TOFPET scanner currently under construction at our institution.

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Nuclear Science, IEEE Transactions on  (Volume:29 ,  Issue: 1 )