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An experiment has been carried out to determine pathological and longevity effects caused by chronic microwave irradiation of mice. Two hundred males were exposed daily for 59 weeks to 0.100 w/cm2 for 4.5 minutes. This treatment produced an average body temperature rise of 3.3Â° C. Histopathology was performed on all dead mice in both irradiated and control group. Changes in body weight, in body temperature response to heating, and in the blood picture were not evident. Testicular degeneration in the form of tubule atrophy and neoplasms of the white cells were indicated. Longevity of the mice did not appear to be affected under the prevailing conditions.