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Fuzzy set theory has a number of properties that make it suitable for formalizing the uncertain information upon which medical diagnosis and treatment is usually based. Firstly, it defines inexact medical entities as fuzzy sets. Secondly, it provides a linguistic approach with an excellent approximation to texts. Finally, fuzzy logic offers reasoning methods capable of drawing approximate inferences. These facts suggest that fuzzy set theory might be a suitable basis for the development of a computerized diagnosis system. This is verified by trials performed with the medical expert system CADIAG-2, which uses fuzzy set theory to formalize medical relationships and fuzzy logic to model the diagnostic process.