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Novel Optoelectronic Platform using an Amorphous/Nanocrystalline Silicon Biosensor for the Specific Identification of Unamplified Nucleic Acid Sequences Based on Gold Nanoparticle Probes

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7 Author(s)
Silva, L.B. ; Univ. Nova de Lisboa, Caparica ; Baptista, P. ; Raniero, L. ; Doria, G.
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Here we describe an innovative optoelectronic platform which enables the specific detection of unamplified nucleic acid sequences with the integration of oligonucleotide-derivatized gold nanoparticles, a colour sensor and a light emission source for a colorimetric detection method. This new low cost, fast and simple optoelectronic platform permits detection of less than 1 picomole quantities of nucleic acid without target or signal amplification.

Published in:
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International

Date of Conference: 10-14 June 2007

Page(s):
935 - 938
E-ISBN :
1-4244-0842-3
Print ISBN:
1-4244-0842-3
INSPEC Accession Number:
9828628
Conference Location :
Lyon
Digital Object Identifier :
10.1109/SENSOR.2007.4300285
Product Type:
Conference Publications

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