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The Effects of Desiccation on Skull Bone Sound Speed in Porcine Models

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4 Author(s)
White, P.J. ; Harvard Medical Sch., Boston ; Palchaudhuri, S. ; Hynynen, K. ; Clement, G.T.

Pre- and postdesiccation sound speeds through ex vivo porcine skull specimens were determined by time-of-flight measurements with propagated broadband pulses centered at 0.97 MHz (Phis12.7 mm, -6-dB bandwidth = 58%). The measured longitudinal sound speed in the 13 porcine samples (predesiccation average sound speed = 1727 plusmn 57 ms-1) changed by a statistically significant +2.3% after deionized water reconstitution (paired t-test, alpha = 0.05, p = 0.0332).

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Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on  (Volume:54 ,  Issue: 8 )