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Behaviour of Human Umbilical Vein Endothelial Cells (HUVEC) Cultivated in Microfluidic channels

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5 Author(s)
Mulder, P.P.M.F.A. ; Res. Inst. of Pharmacy, Groningen Univ. ; Molema, G. ; Koster, S. ; van der Linden, H.J.
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Our long-term goal is to develop advanced tools for cell studies and analysis based on microfluidic systems. In this paper, we report on endothelial cell cultivation in microchannels and 96-well tissue plates, and compare cell phenotype and cellular status in the two environments This was done under both pro-inflammatory conditions (cell stimulation in the presence of the cytokine, Tumour Necrosis Factor, TNFalpha) and normal (medium only) conditions. In addition, we considered the behaviour of cells in a pro-inflammatory environment in the presence of an anti-inflammatory drug

Published in:
Microtechnologies in Medicine and Biology, 2006 International Conference on

Date of Conference: 9-12 May 2006

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