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A new injectable tissue engineered scaffold for regenerative medicine

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3 Author(s)
Hosseinkhani, H. ; Int. Center for Young Scientists, Nat. Inst. for Mater. Sci., Tsukuba ; Hosseinkhani, M. ; Kobayashi, H.

The failure of the application of tissue engineering in clinical trials is questionable. Tissue-engineering scaffolds used in tissue regeneration have micron structures that fail to be analogous to native extracellular matrix (ECM) in terms of both chemical composition and physical structure as a suitable surface structure for cell attachment, proliferation, and differentiation. In this study we designed an artificial ECM in order to mimic the nano-structured topography created by ECM components of native tissue. Selective differentiation of cardiomyocytes cells by self assembly of peptide-amphiphile nanofibers was studied for in vivo cardiac infarction therapy

Published in:
Microtechnologies in Medicine and Biology, 2006 International Conference on

Date of Conference: 9-12 May 2006

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