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Dynamic Cell and Microparticle Control via Optoelectronic Tweezers

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9 Author(s)
Ohta, A.T. ; California Univ., Berkeley ; Pei-Yu Chiou ; Han, T.H. ; Liao, J.C.
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This paper reports on cell and microparticle manipulation using optically induced dielectrophoresis. Our novel optoelectronic tweezers (OET) device enables optically controlled trapping, transportation, and sorting via dielectrophoretic forces. By integrating a spatial light modulator and using direct imaging, arbitrary dynamic manipulation patterns are obtained. Here, we demonstrate manipulation functions, including particle collectors, single-particle traps, individually addressable single-particle arrays, light-defined particle channels, and size-based particle sorting. OET-induced particle manipulation velocities are analyzed as a function of the applied voltage, optical pattern linewidth, and single-particle trap dimensions.

Published in:

Microelectromechanical Systems, Journal of  (Volume:16 ,  Issue: 3 )

Date of Publication:

June 2007

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