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In this paper, we propose spectral analysis method to identify periodically expressed genes in microarray data using a forward and backward linear prediction (FBLP) model and the singular value decomposition (SVD) (FBLP-SVD) algorithm. The spectrum-mean-subtraction method is employed prior to this analysis as a pre-filtering procedure. The combination of the spectrum-mean-subtraction and FBLP-SVD algorithm offers a effective tool for periodicity identification. Using our technique, more genes have been successful identified as periodic genes in the genome of Saccharomyces cerevisiae.
Systems, Man and Cybernetics, 2006. SMC '06. IEEE International Conference on (Volume:2 )
Date of Conference: 8-11 Oct. 2006