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Finding Transcription Factor Binding Sites with Indels

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4 Author(s)
Wangsen Feng ; Sch. of EECS, Peking Univ., Beijing ; Lusheng WAng ; Wanling Qu ; Hanpin Wang

Finding transcription factor binding sites is of great importance for biologists to understand gene expression regulatory mechanisms. Usually, researchers design algorithms to detect transcription factor biding sites with substitution mutations only, based on the conserved property of biological functional sequences. In this paper, we propose a randomized algorithm to find biding sites with indels. A tool is also developed to evaluate the performance of the algorithm based on simulated datasets.

Published in:

Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on

Date of Conference:

6-8 July 2007