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Influence of Formaldehyde on the Expression of Rab26 Gene in HEK293 Cell in Vitro

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4 Author(s)
Jiang Ying ; Coll. of Life Sci., Huazhong Normal Univ., Wuhan ; Bao Lifeng ; Wu Kai ; Yuan Junlin

In this study HEK293 cell was treated with HCHO (ges 250 mu M) of different concentrations and Rab26 gene expression was examined by using RT-PCR method. The results showed that with the elevation of the concentrations of HCHO, the amount of DNA-protein crosslink (DPC) was significantly enhanced (P< 0.01). Meanwhile, accompanied with the elevation of DPC amount after HCHO treatment, the amount of replication and transcription of Rab26 was reduced as examined by PCR and RT-PCR method.

Published in:

Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on

Date of Conference:

6-8 July 2007