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Approaches to Validating the "Quantity" in Quantitative MR Cerebral Perfusion Studies

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6 Author(s)
Smith, M.R. ; Electrical and Computer Engineering, University of Calgary, Calgary, Canada; Radiology, University of Calgary, Calgary, Canada. ; Miller, J. ; Ko, L. ; Chen, J.
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Stroke is a major killer across the world; with staggering financial implications. Magnetic resonance dynamic susceptibility contrast studies are a plausible approach to provide quantitative cerebral blood flow (CBF) measurements. However, what is the correct approach to take when a proven method from another scientific area is suggested as a means for a minor increase in CBF accuracy, but leads to results that totally disagree with the established literature? Agile methodologies are being introduced into business as a new "light-footed" approach to developing software with considerable success. We describe our experiences of adapting Agile software engineering practices to establish a repeatable hardware-software co-design framework for biomedical algorithm validation.

Published in:

Advances in Medical, Signal and Information Processing, 2006. MEDSIP 2006. IET 3rd International Conference On

Date of Conference:

17-19 July 2006