Cart (Loading....) | Create Account
Close category search window
 

1A-4 Acoustoelectric Detection of Current Flow in a Neural Recording Chamber

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Witte, R.S. ; Dept. of Biomed. Eng., Michigan Univ., Ann Arbor, MI ; Olafsson, R. ; O'Donnell, M.

Acoustic pressure (P) traveling in a biologic fluid or tissue generates a local change in electrical conductivity. This acoustoelectric interaction (AE) induces a voltage modulation that depends on local current, resistance, and pressure. We explore the AE signal as a way to enhance traditional electrophysiology or surface recording of neural signals. A thin stretch tube mimicking an enlarged axon and an abdominal segment of a fresh lobster nerve cord were used as test structures for AE detection in a tri-compartment neural recording chamber. Stimulating electrodes passed low frequency current through the structures, while a pair of recording electrodes detected the high frequency AE signal. Ultrasound transducers from 0.5 to 7.5 MHz delivered P up to 2 MPa. The differentially-recorded AE signal was captured on a fast data acquisition board and saved for post processing. In the lobster nerve cord, the AE signal was linear between the tested range of current densities of 9 to 86 mA/cM2 [18 dB/log(J), r 2=0.96] and P of 0.5 to 2 MPa [21 dB/log(P), r 2 =0.96]. In addition, a transverse scan of the structures produced cross-sectional AE images of current flow with remote detection by the recording electrodes. Results were consistent with AE simulations. This study demonstrates that the AF signal can be used to detect and image current flow in a biologic environment with physiologically relevant current densities and acoustic pressures on par with clinical ultrasound imaging

Published in:

Ultrasonics Symposium, 2006. IEEE

Date of Conference:

2-6 Oct. 2006

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.