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Crosstalk phenomena and pulse propagation in metallic and superconducting coupled microstrip lines on insulating and semiconducting substrates are analysed in this communication. Propagation characteristics of these lines are obtained by a numerical formulation which is an extension of the well known Spectral Domain Approach in order to simulate the nature of the strips and to avoid the errors involved by the use of analytical model or TEM approximation. Time domain results are determined by a conventional fast Fourier transform. Effects of the lossy nature and the thickness of the strips, semiconducting layer, substrate thickness, lines length, loading impedances, on crosstalk and transfer are investigated.